What Is BPC-157 TB500 Blend 20mg?

BPC-157 TB500 Blend 20mg is a lyophilised dual-peptide research compound supplied as a white powder in a sealed vial, containing 10mg of BPC-157 and 10mg of TB-500 at a 1:1 ratio. This high-yield 20mg format is intended for preclinical studies requiring extended investigation of combined peptide activity across multiple biological pathways. BPC-157 (Body Protection Compound 157) is a synthetic 15-amino-acid gastric pentadecapeptide with molecular formula C₂H₉₈N₁₆O₂₂, molecular weight 1,419.535 g/mol, and CAS number 137525-51-0 (PubChem CID 9941957). TB-500 is a synthetic fragment of Thymosin Beta-4, a 43-amino acid protein with molecular formula C₂₁₂H₃₅₀N₅₆O₇₈S, molecular weight 4,963.44 g/mol, and CAS number 885340-08-9 (PubChem CID 62707662). All batches of BPC-157 TB500 Blend 20mg are independently verified at ≥99% purity by HPLC and mass spectrometry — results available on our Certificate of Analysis page. For research use only.

BPC-157 & TB500 BLEND 20MG: Key Research Facts

Dual-Pathway Research in a Single Vial

The BPC-157 TB500 Blend 20mg provides researchers with two mechanistically distinct peptides in a single, high-concentration formulation. BPC-157 exerts its primary effects through growth hormone receptor (GHR) upregulation in tendon fibroblasts, VEGFR2-mediated angiogenesis, nitric oxide pathway modulation, and collagen synthesis stimulation. TB-500 acts via a fundamentally different mechanism: it sequesters G-actin through its conserved LKKTET motif, regulating cytoskeletal dynamics to drive cell migration, proliferation, and differentiation at injury sites. By combining both compounds at equal doses, the BPC-157 TB500 Blend 20mg allows researchers to simultaneously investigate complementary repair signalling without running parallel experiments on separate cohorts — reducing both experimental complexity and material cost per study.

BPC-157 Component — Research Profile

BPC-157 has been extensively studied in in vivo models of tendon, ligament, muscle, bone, and gastrointestinal tissue injury. It is notable for its high chemical stability — unlike many peptides, BPC-157 retains activity across a wide pH range and in the presence of gastric acid. Published preclinical data indicates upregulation of early growth response protein 1 (EGR1) in fibroblast cultures, accelerated collagen type I deposition, and promotion of blood vessel formation in wound bed models. A comprehensive review of BPC-157’s healing mechanisms is available on PubMed Central (PMC8228050).

TB-500 Component — Research Profile

TB-500 is the 17-23 amino acid fragment of Thymosin Beta-4 (Tβ4), a ubiquitous actin-sequestering protein expressed in virtually all mammalian cells at high concentrations. As the biologically active domain of the full-length protein, TB-500 retains the capacity to upregulate cell-surface actin, promote angiogenesis, reduce acute and chronic inflammation, and support cardiac and skeletal muscle repair in preclinical models. Research published in Applied Sciences (2026) provides a current scoping review of TB-500 and Thymosin Beta-4 across tissue healing, regeneration, and musculoskeletal repair models, confirming its continued relevance as a research peptide.

Why Choose the 20mg Format?

The BPC-157 TB500 Blend 20mg is suited to research protocols requiring larger sample sets, longer-duration study windows, or dose-escalation designs. At 10mg per peptide component, the BPC-157 TB500 Blend 20mg allows researchers to prepare a greater number of reconstituted aliquots from a single vial compared to the 10mg format, improving batch-to-batch consistency and reducing reconstitution frequency. The lyophilised powder format ensures stability during storage and extends usable shelf life when kept at −20°C. Researchers running comparative studies between isolated peptides and the BPC-157 TB500 Blend 20mg will find the higher vial content particularly advantageous for multi-arm experimental designs.

Storage & Handling

Store BPC-157 TB500 Blend 20mg lyophilised powder at −20°C, protected from light and moisture. Reconstitute using bacteriostatic water or sterile saline immediately prior to use. Once reconstituted, store at 4°C and use within 28 days. Do not refreeze reconstituted solution. Handle under sterile laboratory conditions. This compound is not approved for human use.

Technical Specifications

Related Research Peptides

• BPC-157 10mg — isolated BPC-157 for single-peptide research protocols
• TB-500 5mg — isolated TB-500 for Thymosin Beta-4 pathway studies
• GHK-Cu 50mg — copper peptide studied for tissue remodelling and collagen synthesis
• Ipamorelin 5mg — GH secretagogue used in recovery and cellular repair research
• Selank 10mg — tuftsin-analogue neuropeptide studied alongside regenerative compounds