Where to Buy MOTS-c in the UK
MOTS-c is a comparatively new research compound, and UK availability outpaced documentation standards. This guide covers the analytical data a supplier should publish, the vial and pen options available, and UK delivery and storage.
Lot-matched COAMass-spec identityNext working day UKDiscreet outer packaging
MOTS-c is a mitochondrial-derived peptide encoded in mitochondrial DNA rather than the nuclear genome, which makes it unusual among research peptides. It is investigated in metabolic signalling and cellular energy models. It is supplied as a lyophilised powder in a sealed vial, and as a pre-filled research pen.
Classification
Mitochondrial-derived peptide
Format supplied
pre-filled pen or vial
Origin
Encoded by mitochondrial DNA rather than nuclear DNA
Residue count
16 amino acids, methionine-containing
Purity specification
99% minimum by HPLC with the trace included in the batch pack
Research use only
Not a medicine. Not for human or veterinary consumption.
MOTS-c is supplied in two lyophilised vial sizes. The larger vial is cheaper per milligram but commits you to a single reconstitution, so match it to the length of your run.
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MOTS-c is a mitochondrial-derived peptide, and it is short, hydrophobic and awkward to purify. Those three properties dictate the checks.
MOTS-c sticks to surfaces and to itself. A supplier who cannot tell you the peptide content, as opposed to the HPLC purity, may not know how much peptide actually survived into the vial.
The sequence contains methionine, which oxidises. A COA with an analysis date close to your order date matters more here than on an oxidation-resistant peptide, because the profile drifts on the shelf.
MOTS-c does not always dissolve cleanly in plain bacteriostatic water at higher concentrations. A supplier who has actually handled the compound will tell you this before you order rather than after.
Listings that lean on mitochondrial language and provide no analytical data are selling a story. The only things worth reading are the chromatogram, the mass-spec confirmation and the lot number.
This compound is sold for in-vitro and laboratory research only. It holds no UK marketing authorisation and must not be administered to humans or animals.
Most MOTS-c complaints are dissolution problems misread as potency problems.
Reconstitute at a lower concentration than you would a hydrophilic peptide, then concentrate if needed. Forcing a high concentration produces visible haze and unrecoverable aggregate.
Because of the methionine content, minimise headspace air and time on the bench. Cap immediately and return the vial to refrigeration between uses.
Use low-binding tips and glass where possible. A hydrophobic 16-mer left in standard polypropylene loses a measurable fraction of its nominal concentration to the plastic.
Same working day dispatch before the cut-off, tracked, plain outer packaging, fast UK & EU delivery from Arma Nova Pharma, and 48-hour photographic damage cover.
Yes, for laboratory research. It is not a licensed medicine and must not be supplied or used for human or veterinary consumption. Research purchase is lawful; intended use is the purchaser’s responsibility.
A peptide encoded within mitochondrial DNA rather than the nuclear genome. MOTS-c is among the most studied of this small class, which is why it appears in metabolic and cellular-stress research models.
Almost always concentration. MOTS-c is hydrophobic and will not go fully into solution in plain bacteriostatic water at high loads. Dissolve more dilute and warm gently to room temperature before assessing.
It is encoded in mitochondrial DNA rather than nuclear DNA, which is why it is described as a mitochondrial-derived peptide. That places it in a different category from synthetic analogues and secretagogues.
Yes — the same compound at the same 99% minimum HPLC specification. The pen arrives pre-filled and requires no reconstitution; the vial contains lyophilised powder and gives control over concentration.
The methionine residue is susceptible, so sealed vials should be kept cold and dark and reconstituted solution should have minimal air exposure. This is a real difference from peptides with no oxidisable residues.
A batch-specific Certificate of Analysis carrying the lot number on your vial, the analysis date, the method, the testing laboratory, the HPLC chromatogram and mass-spectrometry identity confirmation.
Yes, inside 14 days of receipt while unopened and in original sealed packaging. Unsealed vials are excluded for health-protection reasons; statutory rights on faulty goods are unaffected.
Closely related compounds, with the same purity, documentation and delivery detail.