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Research Use Only!
UK Buying Guide
Where to Buy IGF-1 LR3 in the UK
IGF-1 LR3 is a recombinant protein rather than a short synthetic peptide, which changes both the analytical requirements and the handling. This guide explains what to look for.
Independent lab testingBatch chromatogramDispatch before cut-offNo indication of contents
Due Diligence
IGF-1 LR3 Is a Recombinant Protein, Not a Synthetic Peptide
IGF-1 LR3 is expressed in a host organism rather than assembled on a resin. That changes the entire documentation set you should expect.
- STEP 01
Expect Bioactivity, Not Just Purity
A recombinant protein has to be folded correctly to be what it claims. HPLC purity says nothing about folding, so ask whether bioactivity or correct disulfide pairing was assessed.
- STEP 02
Endotoxin Testing Is Relevant Here
Because the protein is expressed in bacteria, residual endotoxin is a real consideration in a way it never is for a solid-phase synthetic peptide. A supplier who has never been asked will not have the data.
- STEP 03
LR3 Means a Specific Modification
Long R3 IGF-1 carries an arginine substitution at position three and a 13-residue N-terminal extension. Plain IGF-1 is a different, cheaper protein. The mass difference is large and easily confirmed.
- STEP 04
Aggregation Is the Failure Mode
Proteins aggregate where peptides degrade. Ask whether the batch was checked for aggregate content, because aggregated material can pass a purity assay while being functionally useless.
Research use only. Nothing on this page is medical advice, and no therapeutic claim is made or implied for any compound listed.
Overview
What Is IGF-1 LR3?
IGF-1 LR3 (Long R3 IGF-1) is a modified recombinant analogue of insulin-like growth factor 1, altered at the third position and extended at the N-terminus to increase stability in research conditions. As a 70-plus-residue protein rather than a short peptide, it is more sensitive to handling and requires stricter cold-chain control. It is supplied as a pre-filled research pen.
Classification
Recombinant IGF-1 analogue
Format supplied
pre-filled pen
Production route
Recombinant expression, not solid-phase peptide synthesis
LR3 modification
Arg substitution at position 3 plus a 13-residue N-terminal extension
Purity specification
HPLC assay, 99% minimum, chromatogram provided on request and with the order
Research use only
Not a medicine. Not for human or veterinary consumption.
Available Options
IGF-1 LR3 Options Available From Arma Peptides
IGF-1 LR3 is supplied as a single lyophilised vial. Because it is a folded protein rather than a synthetic peptide, buy to match a specific run rather than holding reconstituted stock.
Product
Format
Size
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Stock
Handling & Delivery
Handling a Recombinant Protein
IGF-1 LR3 is the most fragile item in this catalogue, and it needs protein handling discipline rather than peptide habits.
Never Vortex or Shake
Mechanical shear unfolds proteins. Swirl gently or invert slowly. This is the single most common way a good batch is destroyed in the first minute.
Use an Appropriate Diluent
Follow the batch reconstitution guidance rather than defaulting to bacteriostatic water at any concentration. Protein solubility and stability are pH dependent in a way short peptides are not.
Aliquot Immediately, Freeze Once
Split the reconstituted protein into single-use aliquots before freezing. A second freeze–thaw on a recombinant protein causes aggregation you cannot reverse.
Cold Chain and Tracked Dispatch
Packed with cold protection and shipped tracked in plain outer packaging, same working day before the cut-off, with fast UK & EU delivery from Arma Nova Pharma.
FAQ
IGF-1 LR3 in the UK: Questions Researchers Ask Before Ordering
+Is IGF-1 LR3 legal to buy in the UK?
Yes, as a laboratory research reagent. It is not a licensed medicine and must not be supplied or used for human or veterinary consumption.
+What does LR3 mean?
Long R3 — an arginine substitution at position three combined with a 13-residue N-terminal extension. These modifications distinguish it from native IGF-1, which is a different and cheaper product.
+Why does it matter that this is recombinant?
Because a folded protein can be pure and still be wrong. Correct folding and disulfide pairing determine whether the material behaves as IGF-1 LR3, and neither is measured by an HPLC purity figure.
+Why is IGF-1 LR3 handled differently from short peptides?
It is a recombinant protein of over seventy residues, so it is far more susceptible to denaturation from temperature cycling and agitation than a short synthetic peptide. Cold-chain integrity matters more here than almost anywhere in the catalogue.
+What does LR3 refer to?
Long R3 — a substitution at the third amino acid position combined with an N-terminal extension, both intended to increase stability compared with unmodified IGF-1.
+Can I reconstitute it like a normal peptide?
Not casually. Follow the batch guidance on diluent, dissolve without any agitation, and never vortex. Shear and foaming unfold protein irreversibly.
+How should it be stored?
Sealed lyophilised protein at −20 °C. Once reconstituted, aliquot immediately, refrigerate for short-term use or freeze single-use portions, and thaw each one only once.
+What are the return terms?
Unopened vials in original sealed packaging may be returned within 14 days of receipt. Unsealed vials are excluded for health-protection reasons; statutory rights on faulty or misdescribed goods remain.
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